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2013, Mar;2(1):2228
Quiescent T cells exhibit reduced glycolysis rates and diminished glutamine metabolism to support crucial biosynthetic pathways essential for survival [129]
Pre-treatment with MgSO 4 attenuated the loss of oligodendrocyte markers, such as myelin basic protein (MBP) and oligodendrocyte transcription factor (Olig2), in ipsilateral white matter and decreased the number of microglia, preventing thus cell death of pre-oligodendrocytes (Seyama et al., 2018)
They mainly act by binding directly to the enzyme or by interacting with copper molecules in its active site